Journal: American journal of hypertension
Article Title: Dietary Menthol Attenuates Inflammation and Cardiac Remodeling After Myocardial Infarction via the Transient Receptor Potential Melastatin 8.
doi: 10.1093/ajh/hpz162
Figure Lengend Snippet: Figure 5. The expression of cytokines and chemokines in the infarcted zone. TNF-α (A), IL-1β (B), and IL-6 (C) concentrations were analyzed by ELISA kits. (D) MCP-1 expression was detected by ELISA kits. WT, wide-type mice; TRPM8 KO, TRPM8 knockout mice; MI, myocardial infarction; Ment, menthol; TNF-α, tumor neurosis factor α; IL-1β, interleukin 1β; IL-6, interleukin 6; MCP-1, monocyte chemoattractant protein 1. Presented values are mean ± SEM. n = 6–8/group. #P < 0.01 vs. Sham + Cont; **P < 0.05 vs. MI + Cont; ##P < 0.01 vs. MI + Cont.
Article Snippet: Commercially available mice CGRP and substance P (SP) ELISA kits (R&D Systems) were used for determination of SP and CGRP release, which was normalized by the heart weight.
Techniques: Expressing, Enzyme-linked Immunosorbent Assay, Knock-Out